logo
Question of the Week
Video Library
Ophthalmology Books & Manuals
Cybersight Atlas of Eye Diseases
The Ophthalmology Minute
Nursing Education
Eye Care Equipment
Orbis Program Features
Free Online Journals
Ophthalmology Links
Frequently Asked Questions (FAQ)
Print ViewPrint this Page
Lacrimal Duct Defect to Lymphoid Hyperplasia -  

Lymphoid Hyperplasia
Lecture 52 of 52  NEXT»

(Reactive Lymphoid Hyperplasia; Lymphoid Tumors; Malignant Lymphoma; Pseudolymphoma; Pseudotumor; Burkitt Lymphoma; Neoplastic Angioendotheliomatosis)

General: Occurs in tropical Africa; young children; idiopathic orbital inflammation; systemic disease is rarely associated but occasionally occurs with either vasculitis or lymphomas; etiology of Burkitt lymphoma currently includes three factors: (i) Epstein-Barr virus, (ii) malaria, and (iii) chromosomal translocations activating the c-myc oncogene, which induces uncontrolled B-cell proliferation.
Ocular: Proptosis; extraocular motility disturbances; lesions of orbit, lacrimal gland, conjunctiva, and uvea; cortical blindness; retinal artery occlusion; retinal vascular and pigment epithelial alterations; vitreitis.
Clinical: Maxillary tumor; Epstein-Barr virus; cranial neuropathy.

Brooks HL, et al. Orbital Burkitt's lymphoma in a homosexual man with acquired immune deficiency. Arch Ophthalmol 1984; 102:1533-1537.
Cheung MK, et al. Diagnosis of reactive lymphoid hyperplasia by chorioretinal biopsy. Am J Ophthalmol 1994; 118: 457-462.
Liesegang TJ. Ocular adnexal lymphoproliferative lesions. Mayo Clin Proc 1993; 68:1003-1010.
de The G. The etiology of Burkitt's lymphoma and the history of the shaken dogmas. Blood Cells 1993; 19:667-673.
Donoso LA. Meningeal carcinomatosis secondary to malignant lymphoma (Burkitt's pattern). J Pediatr Ophthalmol Strabismus 1981; 18:48-50.
Elner VM, et al. Neoplastic angioendotheliomatosis. Ophthalmology 1986; 93:1237-1245.
Gaidano G, Dalla-Favera R. Biologic and molecular characterization of non-Hodgkin's lymphoma. Curr Opin Oncol 1993; 5:776-784.
Jakobiec FA, et al. Clinicopathologic characteristics of orbital lymphoid hyperplasia. Ophthalmology 1979; 86: 948-966.

Previous Section

Table of Contents

Next Section


Lecture 52 of 52 «Previous Lecture   1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52    Next»